The probe is directed at all CAR-Ts currently ... positive lymphoma – in patients who had received both types of CAR-T therapy. The regulator highlighted the products by name, including Bristol- ...

CAR T-cell therapy carried a risk of second primary malignancy (SPM) that was no worse than that of other standard-of-care (SOC) cancer therapies, according to a systematic literature review and ...

Chimeric antigen receptor (CAR) T cell therapy is an immunotherapy. It uses a patient’s own immune system to fight certain blood cancers. Normal T cells can “hook” onto cancer cells and kill them, but ...

In January 2024, the U.S. Food and Drug Administration (FDA) required labeling information for all currently available CAR ...

The frequency of second primary malignancies (SPMs) arising in cancer survivors following treatment with CAR T-cell therapy was statistically comparable to the frequency of SPMs following other ...

Like other CAR-Ts, Calibr's therapy is manufactured from a patient's own T-cells, which are harvested and genetically modified to fight cancer before being reintroduced into the body. However ...

Chimeric antigen receptor T-cell therapy, or CAR-T cell therapy, is one type of immunotherapy. Sometimes likened to a “smart drug” or “living drug,” CAR-T cell therapy relies on ...

“It’s basically a death sentence,” explains June, who led a team that pioneered the first CAR T-cell therapy to treat certain blood cancers. Pediatricians “basically say, ‘Go ...

The Food and Drug Administration is investigating a possible link between patients developing new cancers after undergoing ...

Matt LeBlanc, the star of Friends, was seen in looking unrecognizable in Los Angeles following the tragic overdose death of ...

In South Carolina, Deputy Jamel Bradley remained a school resource officer despite complaints that he was preying on girls at ...

When the symptoms and inflammation are not brought under control, they can cause organ damage. Like other cell therapies, CAR T cell therapy uses a modified cell either from the patient or from a ...