Inter Miami were dealt a huge injury blow as star player Lionel Messi was withdrawn during their victory over Toronto. It now appears that Messi will miss Miami’s next game against Orlando City, and could even miss the upcoming U.

Lionel Messi is back as Inter Miami resumes its MLS playoff push. Messi was listed in the starting lineup for Wednesday’s match against Toronto.

Inter Miami's star forward Lionel Messi is in doubt for the upcoming U.S. Open Cup final, as confirmed by Inter Miami head coach Tata Martino

Messi was subbed off in the 37th minute of Inter Miami's match against Toronto, after spending a few minutes laboring with what appeared to be a leg issue. He was stretching during play, then eventually took off his captain's armband and simply waited for play to stop so he could depart.

After Inter Miami’s 4-0 win vs Toronto, Martino announced that Messi and teammate Jordi Alba will not play Sunday vs Orlando City. Messi previously missed the team’s match on September 16 against Atlanta due to muscle fatigue.

Inter Miami's acquisition of Lionel Messi, Sergio Busquets, and Jordi Alba is transforming MLS, with Pedro hailing their "great choice"

Messi fever has gripped the United States from Miami to LA, from pitch invaders to Hollywood stars, writes Lawrence Ostlere. But can Major League Soccer seize the moment?

Inter Miami are expected to be without Lionel Messi on Saturday against Atlanta United with the seven-time Ballon d'Or winner dropping a hint over his absence on social media

Inter Miami showed dominance Wednesday, extending a 12-game unbeaten streak with Lionel Messi in its lineup. But the Herons' shutout was soured when the Argentine departed because he aggravated an injury.

Check out this article for our top Toronto FC vs. Inter Miami prediction for Wednesday, the latest betting odds and an update on Lionel Messi’s injury.

Lionel Messi was subbed off with an injury in the first half of Inter Miami's 4-0 win against Toronto FC in MLS action on Wednesday.