The White House chief of staff, Susie Wiles, delivered a series of unusually candid and at times unflattering assessments of President Donald Trump, his second-term agenda and some of his closest allies in a series of wide-ranging interviews with Vanity Fair published Tuesday.

A Trump administration official made a dire prediction during a recent photoshoot for Vanity Fair, the magazine behind Tuesday’s bombshell coverage of the president’s inner circle.

But in a series of 11 interviews for Vanity Fair over the past year with author Chris Whipple, she spoke candidly about how she wields power inside the White House and offered reflections on Trump’s p...